Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22518663 | 0.83 | SPHK1 (0.39) | SPHK1GPR84FFAR1LMNAMAPT | |
| SCHEMBL11802457 | 0.83 | GPR84 (0.47) | SPHK1GPR84FFAR1LMNAMAPT | |
| SCHEMBL11796216 | 0.83 | GPR84 (0.47) | SPHK1GPR84FFAR1LMNAMAPT | |
| SCHEMBL8830375 | 0.83 | GPR84 (0.47) | SPHK1GPR84FFAR1LMNAMAPT | |
| SCHEMBL11795745 | 0.83 | GPR84 (0.47) | SPHK1GPR84FFAR1LMNAMAPT | |
| SCHEMBL28374932 | 0.83 | GPR84 (0.39) | SPHK1GPR84FFAR1LMNAMAPT | |
| SCHEMBL3794736 | 0.83 | OPRM1 (0.41) | SPHK1GPR84LMNAOPRM1SMPD1 | |
| SCHEMBL3789364 | 0.83 | OPRM1 (0.41) | SPHK1GPR84LMNAOPRM1SMPD1 | |
| SCHEMBL7984389 | 0.82 | SPHK1 (0.41) | SPHK1GPR84FFAR1LMNAMAPT | |
| SCHEMBL8986589 | 0.82 | TSHR (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572910-B1 | Polysaccharide ether dialysis membrane | AKZO NOBEL NV (NL) | 1996-06-26 | — | — | EP | claimed |
| EP-0572910-A1 | Polysaccharide ether dialysis membrane | Akzo Nobel N.V. (NL) | 1993-12-08 | — | — | EP | claimed |
| EP-0572910-B1 | Polysaccharide ether dialysis membrane | AKZO NOBEL NV (NL) | 1996-06-26 | — | — | EP | disclosed |
| EP-0572910-A1 | Polysaccharide ether dialysis membrane | Akzo Nobel N.V. (NL) | 1993-12-08 | — | — | EP | disclosed |