SCHEMBL8986641

SCHEMBL8986641

C=CCOC(=S)NN.NNC(O)=S

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22638031 0.94
SCHEMBL8986645 0.76 MAPT (0.31) ALDH1A1TSHRMAPTCACNA1BAPBA1
SCHEMBL9298876 0.75 MAPT (0.39) ALDH1A1TSHRMAPTCACNA1BAPBA1
SCHEMBL9737808 0.71 CA12 (0.39) ALDH1A1MAPT
SCHEMBL1692037 0.70 ALDH1A1 (0.48) ALDH1A1TSHRMAPTCACNA1BAPBA1
SCHEMBL1076725 0.69
SCHEMBL20897913 0.69 MAPT (0.39) ALDH1A1TSHRMAPTCACNA1BAPBA1
SCHEMBL461760 0.69 MAPT (0.39) ALDH1A1TSHRMAPTCACNA1BAPBA1
SCHEMBL11666355 0.68 ALDH1A1 (0.46) ALDH1A1TSHRMAPTCACNA1BAPBA1
SCHEMBL23648278 0.67 MAPT (0.42) ALDH1A1TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602589-B1 Processes for preparation of 5-pyrazolemercaptan derivatives and intermediates thereof LUCKY LTD (KR) 1996-06-26 EP disclosed
US-5468896-A Chemical intermediates for herbicides LUCKY LTD. (KR) 1995-11-21 US disclosed
US-5466854-A From alkyl hydrazine and carbon disulfide LUCKY LTD. (KR) 1995-11-14 US disclosed
US-5416220-A From a dithiocabazate and an ethoxymethylene malonate LUCKY, LTD. (KR) 1995-05-16 US disclosed
US-5405965-A Heating ethylidene dithiocarbazate compound with base LUCKY LTD. (KR) 1995-04-11 US disclosed
EP-0602589-A1 Processes for preparation of 5-pyrazolemercaptan derivatives and intermediates thereof LUCKY LTD. (KR) 1994-06-22 EP disclosed