SCHEMBL9737808

SCHEMBL9737808

CCOC(=S)NN.NNC(O)=S

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
ALDH1A1 P00352 6/20 0.35
KDM4E B2RXH2 4/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260004 0.93
Bromide SCHEMBL4400362 0.90
O-Xylene SCHEMBL9626376 0.85 MAPT (0.41) ALDH1A1KDM4EGAAMAPTMEN1
SCHEMBL9627280 0.85 MAPT (0.41) ALDH1A1KDM4EGAAMAPTMEN1
SCHEMBL6692143 0.74 ALDH1A1 (0.35) CA12CA1CA2CA9ALDH1A1
SCHEMBL29116488 0.73
SCHEMBL18857997 0.73
SCHEMBL26695430 0.73 CA12 (0.40) CA12CA1CA2CA9ALDH1A1
Methane SCHEMBL7549086 0.72 ALDH1A1 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL8986641 0.71 ALDH1A1 (0.35) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5162539-A Reaction of a carboxylic acid with a dithiocarbazic ester in the presence of phosphoryl chloride BAYER AKTIENGESELLSCHAFT (DE) 1992-11-10 US disclosed