Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986849 | 0.85 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8986845 | 0.84 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8986852 | 0.84 | SMN1; SMN2 (0.58) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8986858 | 0.84 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8986883 | 0.84 | KMT2A (0.70) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL8986865 | 0.81 | KMT2A (0.53) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL8986860 | 0.81 | L3MBTL1 (0.72) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL9323081 | 0.80 | NAMPT (0.49) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL9323136 | 0.79 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9321855 | 0.77 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572782-B1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID CO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5354755-A | Agricultural uses | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5276038-A | 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0572782-A1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |