Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986849 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8986852 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8986845 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8986883 | 0.88 | KMT2A (0.70) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8986865 | 0.84 | KMT2A (0.53) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8986838 | 0.84 | NPC1 (0.62) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8986860 | 0.83 | L3MBTL1 (0.72) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL12643828 | 0.83 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9323081 | 0.82 | NAMPT (0.49) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9323136 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572782-B1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID CO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5354755-A | Agricultural uses | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5276038-A | 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-01-04 | — | — | US | disclosed |