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SCHEMBL8986871

SCHEMBL8986871

CCCCCNC(=O)Nn1cnc2ccccc2c1=O

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.71
▸ NPC1 O15118 5/20 0.57
▸ RAB9A P51151 4/20 0.57
▸ KMT2A Q03164 3/20 0.55
▸ MEN1 O00255 1/20 0.55
▸ MAPT P10636 3/20 0.54
▸ SMN1; SMN2 Q16637 4/20 0.54
▸ ALDH1A1 P00352 2/20 0.51
▸ ASAH1 Q13510 1/20 0.51
▸ POLB P06746 1/20 0.51
▸ HTT P42858 3/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ EPHX1 P07099 3/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27712494 0.76 NPC1 (0.67) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL12643828 0.76 NPC1 (0.57) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL15832183 0.76 NPC1 (0.56) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL12643758 0.74 NPC1 (0.54) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL8986849 0.72 SMN1; SMN2 (0.54) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL3563360 0.71 KMT2A (0.80) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL8986858 0.71 SMN1; SMN2 (0.53) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL8986845 0.71 SMN1; SMN2 (0.59) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL8986852 0.71 SMN1; SMN2 (0.58) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL8986883 0.71 KMT2A (0.70) LMNANPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6056798-A — — None — — JP disclosed
JP-6056798-A — — None — — JP disclosed
EP-0717658-A1 POLYMERIC SURFACTANT-ENCAPSULATED MICROBUBBLES AND THEIR USE IN ULTRASOUND IMAGING NYCOMED IMAGING AS (NO) 1996-06-26 — — EP disclosed
EP-0572782-B1 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents AMERICAN CYANAMID CO (US) 1996-06-26 — — EP disclosed
EP-0572782-B1 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents AMERICAN CYANAMID CO (US) 1996-06-26 — — EP disclosed
WO-1995006518-A1 POLYMERIC SURFACTANT-ENCAPSULATED MICROBUBBLES AND THEIR USE IN ULTRASOUND IMAGING NYCOMED IMAGING A/S (NO) 1995-03-09 — — WO disclosed
US-5354755-A Agricultural uses AMERICAN CYANAMID COMPANY (US) 1994-10-11 — — US disclosed
US-5354755-A Agricultural uses AMERICAN CYANAMID COMPANY (US) 1994-10-11 — — US disclosed
US-5354755-A Agricultural uses AMERICAN CYANAMID COMPANY (US) 1994-10-11 — — US disclosed
JP-H0656798-A 1-ARYL-3-(3,4-DIHYDRO-4-OXO-3-QUINAZOLINYL)UREA ANTIBACTERIAL AND FUNGICIDAL AGENT AMERICAN CYANAMID CO 1994-03-01 — — JP disclosed
JP-H0656798-A 1-ARYL-3-(3,4-DIHYDRO-4-OXO-3-QUINAZOLINYL)UREA ANTIBACTERIAL AND FUNGICIDAL AGENT AMERICAN CYANAMID CO 1994-03-01 — — JP disclosed
US-5276038-A 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents AMERICAN CYANAMID COMPANY (US) 1994-01-04 — — US disclosed
US-5276038-A 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents AMERICAN CYANAMID COMPANY (US) 1994-01-04 — — US disclosed
US-5276038-A 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents AMERICAN CYANAMID COMPANY (US) 1994-01-04 — — US disclosed
EP-0572782-A1 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents AMERICAN CYANAMID COMPANY (US) 1993-12-08 — — EP disclosed
EP-0572782-A1 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents AMERICAN CYANAMID COMPANY (US) 1993-12-08 — — EP disclosed
EP-0572782-A1 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents AMERICAN CYANAMID COMPANY (US) 1993-12-08 — — EP disclosed
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