Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634074 | 1.00 | AOC3 (0.44) | AOC3HTR6SLC6A4GAAIDO1 | |
| SCHEMBL4886452 | 0.85 | AOC3 (0.44) | AOC3HTR6SLC6A4GAAIDO1 | |
| SCHEMBL5009193 | 0.85 | AOC3 (0.48) | AOC3HTR6SLC6A4GAAIDO1 | |
| SCHEMBL4864455 | 0.80 | CNR1 (0.42) | AOC3HTR6GAA | |
| SCHEMBL7983773 | 0.76 | L3MBTL1 (0.42) | ACP3 | |
| SCHEMBL5195514 | 0.75 | KIF11 (0.41) | — | |
| SCHEMBL5195520 | 0.75 | KIF11 (0.41) | — | |
| SCHEMBL8986774 | 0.74 | AOC3 (0.39) | AOC3SLC6A4SLC6A2SLC6A3PDE1B | |
| SCHEMBL14587100 | 0.70 | AOC3 (0.64) | AOC3HTR6SLC6A4IDO1TDO2 | |
| SCHEMBL2240456 | 0.70 | ADRB3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717746-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007284-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-03-16 | — | — | WO | disclosed |