SCHEMBL8986961

SCHEMBL8986961

CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987136 0.93 LTB4R (1.00) LTB4R
SCHEMBL8987077 0.92 LTB4R (0.86) LTB4R
SCHEMBL8987115 0.92 LTB4R (1.00) LTB4R
SCHEMBL8987092 0.92 LTB4R (1.00) LTB4R
SCHEMBL8987162 0.92 LTB4R (1.00) LTB4R
SCHEMBL8987468 0.92 LTB4R (0.84) LTB4R
SCHEMBL8987173 0.91 LTB4R (1.00) LTB4R
SCHEMBL8987222 0.91 LTB4R (0.82) LTB4R
SCHEMBL8987063 0.91 LTB4R (0.82) LTB4R
SCHEMBL9291640 0.91 LTB4R (1.00) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed