Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987156 | 0.91 | LTB4R (0.84) | LTB4R | |
| SCHEMBL8986961 | 0.91 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987092 | 0.90 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987468 | 0.89 | LTB4R (0.84) | LTB4R | |
| SCHEMBL8987277 | 0.89 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8986978 | 0.88 | LTB4R (0.81) | LTB4R | |
| SCHEMBL8987403 | 0.88 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987235 | 0.87 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987136 | 0.85 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987115 | 0.84 | LTB4R (1.00) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485822-B1 | Process for preparing high molecular weight polyolefines | HOECHST AG (DE) | 1996-07-03 | — | — | EP | disclosed |
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| EP-0485823-B1 | 2-Substituted bisindenyl-metallocenes, process for their preparation and their use as catalysts for the polymerization of olefins | HOECHST AG (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |
| EP-0540604-A1 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Aventis Pharma S.A. (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0485823-A1 | 2-Substituted bisindenyl-metallocenes, process for their preparation and their use as catalysts for the polymerization of olefins | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-20 | — | — | EP | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |