Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987305 | 1.00 | MAPT (0.56) | MAPTL3MBTL1MEN1USP2ALDH1A1 | |
| SCHEMBL8987018 | 0.84 | LTB4R (0.57) | MAPTL3MBTL1MEN1USP2ALDH1A1 | |
| SCHEMBL8987023 | 0.84 | LTB4R (0.57) | MAPTL3MBTL1MEN1USP2ALDH1A1 | |
| SCHEMBL9119169 | 0.82 | MAPT (0.44) | MAPTL3MBTL1USP2ALDH1A1KDM4E | |
| SCHEMBL9119173 | 0.82 | MAPT (0.44) | MAPTL3MBTL1USP2ALDH1A1KDM4E | |
| SCHEMBL21065452 | 0.78 | MAPT (0.47) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL21065451 | 0.78 | MAPT (0.47) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL21065450 | 0.78 | MAPT (0.47) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL30271653 | 0.75 | MAPT (0.44) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL21128448 | 0.75 | MAPT (0.44) | MAPTMEN1ALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |