Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119173 | 1.00 | MAPT (0.44) | MAPTKDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL8987310 | 0.82 | MAPT (0.56) | MAPTKDM4EUSP2ALDH1A1LTB4R | |
| SCHEMBL8987305 | 0.82 | MAPT (0.56) | MAPTKDM4EUSP2ALDH1A1LTB4R | |
| SCHEMBL21065451 | 0.81 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDLTB4R | |
| SCHEMBL21065452 | 0.81 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDLTB4R | |
| SCHEMBL21065450 | 0.81 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDLTB4R | |
| SCHEMBL9119172 | 0.81 | FAAH (0.43) | MAPTKDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL30271653 | 0.77 | MAPT (0.44) | MAPTKDM4EALDH1A1GLAHPGD | |
| SCHEMBL21128448 | 0.77 | MAPT (0.44) | MAPTKDM4EALDH1A1GLAHPGD | |
| SCHEMBL9485825 | 0.76 | FAAH (0.41) | MAPTKDM4EHSD17B10USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995028929-A1 | AMINOLINE-N-OXIDE ANTIMICROBIALS FOR USE AGAINST H. PYLORI INFECTIONS | RPMS TECHNOLOGY LIMITED (GB) | 1995-11-02 | — | — | WO | disclosed |
| WO-1995028929-A1 | AMINOLINE-N-OXIDE ANTIMICROBIALS FOR USE AGAINST H. PYLORI INFECTIONS | RPMS TECHNOLOGY LIMITED (GB) | 1995-11-02 | — | — | WO | disclosed |
| EP-0374765-B1 | 2,3-Disubstituted-4-hydroxyquinoline derivatives and process for preparing the same | MEIJI SEIKA KAISHA (JP) | 1994-06-22 | — | — | EP | disclosed |