Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321053 | 0.91 | CYP3A4 (0.47) | LMNAPRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL5187222 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL7906767 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL1008681 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL7906758 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL7553699 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL28378208 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL7906801 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL8798951 | 0.83 | NAAA (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL9019436 | 0.82 | CYP2D6 (0.39) | LMNACYP3A4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587169-A | COMPRISING NONIONIC HYDROXYLATED GROUP; PROTECTIVE CREAM | L'OREAL (FR) | 1996-12-24 | — | — | US | claimed |
| US-5587169-A | COMPRISING NONIONIC HYDROXYLATED GROUP; PROTECTIVE CREAM | L'OREAL (FR) | 1996-12-24 | — | — | US | disclosed |