Sugi Predict

Sugi Predict / Compounds / SCHEMBL2321053

SCHEMBL2321053

SCHEMBL2321053

CCCCC(CC)COC(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 5/20 0.47
▸ TSHR P16473 3/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ ATM Q13315 1/20 0.47
▸ ALDH1A1 P00352 6/20 0.43
▸ LMNA P02545 3/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ CA2 P00918 4/20 0.42
▸ RECQL P46063 1/20 0.40
▸ MAPK1 P28482 3/20 0.38
▸ PRSS1 P07477 1/20 0.38
▸ PRSS2 P07478 1/20 0.38
▸ PRSS3 P35030 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ MMP9 P14780 1/20 0.34
▸ MMP8 P22894 1/20 0.34
▸ MMP14 P50281 1/20 0.34
▸ CA1 P00915 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ DUSP3 P51452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987386 0.91 LMNA (0.38) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL7608018 0.80 ALDH1A1 (0.42) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL7906801 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3
SCHEMBL7906767 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3
SCHEMBL1008681 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3
SCHEMBL28378208 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3
SCHEMBL7553699 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3
SCHEMBL7906758 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3
SCHEMBL5187222 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3
SCHEMBL8798951 0.79 NAAA (0.40) TSHRALDH1A1LMNAKDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170181951-A1 ANHYDROUS FOAMING COMPOSITION L'ORÉAL (FR) 2017-06-29 — — US claimed
EP-2661250-B1 ANHYDROUS FOAMING COMPOSITION L'ORÉAL (FR) 2017-05-17 — — EP claimed
EP-2661250-A1 ANHYDROUS FOAMING COMPOSITION L'Oréal (FR) 2013-11-13 — — EP claimed
WO-2012093102-A1 ANHYDROUS FOAMING COMPOSITION L'OREAL (FR) 2012-07-12 — — WO claimed
EP-1333803-B1 USE OF CARBOHYDRATE FOR ENHANCING THE SKIN BARRIER FUNCTION OREAL (FR) 2007-04-25 — — EP claimed
EP-1529523-B1 Cosmetic use of phytantriol as an agent for preventing or reducing the adhesion of microorganisms on the skin and/or mucosal surfaces OREAL (FR) 2006-08-16 — — EP claimed
US-20050238609-A1 Cubic gel particles, uses thereof L'OREAL (FR) 2005-10-27 — — US claimed
US-20050131077-A1 Preventing or reducing the adhesion of microorganisms with phytanetriol L'OREAL (FR) 2005-06-16 — — US claimed
EP-1529519-A2 Cosmetic use of cubic gel particles as agents against adhesion of microorganisms to the skin and/or mucosa L'OREAL (FR) 2005-05-11 — — EP claimed
EP-1529523-A1 Cosmetic use of phytantriol as an agent for preventing or reducing the adhesion of microorganisms on the skin and/or mucosal surfaces L'OREAL (FR) 2005-05-11 — — EP claimed
WO-2001026619-A2 COMPOSITION, IN PARTICULAR COSMETIC, CONTAINING DIHYDROEPIANDOSTERONE (DHEA) AND A DESQUAMATIVE AGENT L'OREAL (FR) 2001-04-19 — — WO claimed
EP-0711540-B1 Cosmetic or dermatologic oil/water dispersion stabilized with cubic gel particles and method of preparation OREAL (FR) 2000-05-10 — — EP claimed
US-5905165-A Alkyl N-(hydroxyalkyl) carbamates and their application in cosmetics, more particularly in hair compositions L'OREAL (FR) 1999-05-18 — — US claimed
US-5788992-A COSMETICS AND HAIR CONDITIONERS L'OREAL (FR) 1998-08-04 — — US claimed
EP-0853472-A1 USE OF CARBOHYDRATES FOR PROMOTING SKIN EXFOLIATION L'OREAL (FR) 1998-07-22 — — EP claimed
US-5756108-A CONTAINING PARTICLES FORMED OF PHYTANETRIOL OR N-2-ALKOXYCARBONYL DERIVATIVE OF N-METHYLGLUCAMINE, WATER SOLUBLE SURFACTANT AS DISPERSING AND STABILIZING AGENT L'OREAL (FR) 1998-05-26 — — US claimed
WO-1997012597-A1 USE OF CARBOHYDRATES FOR PROMOTING SKIN EXFOLIATION L'OREAL (FR) 1997-04-10 — — WO claimed
US-5587169-A COMPRISING NONIONIC HYDROXYLATED GROUP; PROTECTIVE CREAM L'OREAL (FR) 1996-12-24 — — US claimed
EP-0666251-B1 N-hydroxy substituted alkyl carbamates and their use in cosmetics especially in hair-care compositions OREAL (FR) 1996-12-04 — — EP claimed
EP-0711540-A1 Cosmetic or dermatologic oil/water dispersion stabilized with cubic gel particles and method of preparation L'OREAL (FR) 1996-05-15 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131077-A1 Preventing or reducing the adhesion of microorganisms with phytanetriol ICAM1, FABP2, CUTA CYP3A4 3908/4885TSHR 2255/4885TDP1 2453/4885
US-20050238609-A1 Cubic gel particles, uses thereof CUTA, C3AR1, CLSPN CYP3A4 1596/4885TSHR 2656/4885TDP1 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.