Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21018440 | 0.86 | KDM4E (0.54) | KDM4EHPGDALDH1A1HSD17B10TLR9 | |
| Hydrochloric Acid SCHEMBL7471438 | 0.84 | KDM4E (0.45) | KDM4EHPGDALDH1A1HSD17B10TLR9 | |
| SCHEMBL8987601 | 0.83 | MMP2 (0.50) | KDM4EHPGDALDH1A1HSD17B10TLR9 | |
| SCHEMBL20982653 | 0.83 | CHEK2 (0.61) | KDM4EHPGDALDH1A1HSD17B10FLT3 | |
| Hydrochloric Acid SCHEMBL8987782 | 0.81 | KDM4E (0.42) | KDM4EFLT3CHEK2POLBRAB9A | |
| SCHEMBL21017224 | 0.81 | PRSS12 (0.49) | KDM4EHPGDALDH1A1HSD17B10TLR9 | |
| SCHEMBL20982731 | 0.81 | CHEK2 (0.59) | KDM4EHPGDALDH1A1HSD17B10FLT3 | |
| SCHEMBL21017891 | 0.81 | KDM4E (0.49) | KDM4EHPGDALDH1A1HSD17B10TLR9 | |
| SCHEMBL21017865 | 0.80 | PRSS12 (0.51) | KDM4EHPGDALDH1A1HSD17B10TLR9 | |
| SCHEMBL21017885 | 0.80 | PRSS12 (0.51) | KDM4EHPGDALDH1A1HSD17B10TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719765-A2 | Phenylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-03 | — | — | EP | disclosed |