SCHEMBL8987635

SCHEMBL8987635

C=C1c2ccccc2-c2cc(CCCCCC)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.57
LPL P06858 6/20 0.46
LIPG Q9Y5X9 6/20 0.46
TRPV1 Q8NER1 1/20 0.44
MGLL Q99685 1/20 0.44
ESR1 P03372 2/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
TACR2 P21452 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
HTR2A P28223 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
SHBG P04278 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
HSPD1 P10809 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27944146 0.90 GPR3 (0.63) GPR3LPLLIPGTRPV1MGLL
SCHEMBL2937164 0.88 GPR3 (0.49) GPR3LPLLIPGTRPV1MGLL
SCHEMBL9771937 0.81 GPR3 (0.57) GPR3LPLLIPGHTR2AALDH1A1
SCHEMBL8987763 0.79 MAPT (0.58) KDM4EALDH1A1LMNATP53HSD17B10
SCHEMBL918609 0.79 NPC1 (0.64) GPR3LPLLIPGHTR2AALDH1A1
SCHEMBL9062730 0.79 NPC1 (0.64) GPR3LPLLIPGHTR2AALDH1A1
SCHEMBL37031 0.77 NPC1 (0.66) GPR3LPLLIPGHTR2AALDH1A1
SCHEMBL8669846 0.77 SMN1; SMN2 (0.61) GPR3ALDH1A1LMNA
SCHEMBL29531152 0.77 NPC1 (0.66) GPR3LPLLIPGHTR2AALDH1A1
SCHEMBL7933610 0.77 CNR1 (0.57) GPR3LPLLIPGHTR2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400972-B1 Fluorescent degree of cure monitors MINNESOTA MINING & MFG (US) 1996-07-03 EP disclosed
US-5182316-A Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-26 US disclosed
US-5118559-A Dibenzofulvene compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US disclosed
US-5047444-A Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-10 US disclosed
EP-0400972-A2 Fluorescent degree of cure monitors MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP disclosed