SCHEMBL8987763

SCHEMBL8987763

C=C1c2ccccc2-c2cc(CC)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
ALDH1A1 P00352 2/20 0.58
NPC1 O15118 1/20 0.58
LMNA P02545 1/20 0.58
MAPK1 P28482 1/20 0.58
RAB9A P51151 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
PDK2 Q15119 1/20 0.42
TP53 P04637 1/20 0.39
NR1H2 P55055 3/20 0.39
NR1H3 Q13133 3/20 0.39
KIF11 P52732 1/20 0.38
TRPA1 O75762 1/20 0.38
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
CSNK2A3 Q8NEV1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8670753 0.80 MAPT (0.89) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL8987718 0.79 GABRA1 (0.41) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL8987635 0.79 GPR3 (0.57) ALDH1A1LMNATP53KDM4EHSD17B10
SCHEMBL7318179 0.76 NPC1 (0.96) MAPTALDH1A1NPC1LMNAMAPK1
9,10-Phenanthrenequinone SCHEMBL6059381 0.74 NPC1 (0.92) MAPTALDH1A1NPC1LMNAMAPK1
Formaldehyde SCHEMBL28131826 0.74 NPC1 (0.92) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL16884741 0.74 ALDH1A1 (0.51) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL36840 0.73 NPC1 (1.00) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL29352712 0.73 NPC1 (1.00) MAPTALDH1A1NPC1LMNAMAPK1
Anthraquinone SCHEMBL6310187 0.73 NPC1 (1.00) MAPTALDH1A1NPC1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400972-B1 Fluorescent degree of cure monitors MINNESOTA MINING & MFG (US) 1996-07-03 EP disclosed
US-5182316-A Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-26 US disclosed
US-5118559-A Dibenzofulvene compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US disclosed
US-5047444-A Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-10 US disclosed
EP-0400972-A2 Fluorescent degree of cure monitors MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP disclosed