Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP13 | P45452 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7474731 | 0.88 | HRAS (0.43) | MMP2MMP13CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7461628 | 0.79 | HRAS (0.54) | MMP2MMP13CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7476664 | 0.78 | HRAS (0.43) | MMP2MMP13MMP9MMP8CA12 | |
| Hydrochloric Acid SCHEMBL7471854 | 0.78 | HRAS (0.44) | MMP2MMP13CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7470484 | 0.78 | HRAS (0.47) | HDAC6HDAC2HDAC8HDAC1SIRT2 | |
| SCHEMBL8987632 | 0.77 | KDM4E (0.49) | PRSS12 | |
| Hydrochloric Acid SCHEMBL7470261 | 0.76 | HRAS (0.43) | MMP2MMP13CA12CA1CA2 | |
| SCHEMBL21018440 | 0.76 | KDM4E (0.54) | PRSS12 | |
| SCHEMBL7472474 | 0.75 | HRAS (0.42) | PRSS12 | |
| Hydrochloric Acid SCHEMBL7465588 | 0.75 | HRAS (0.46) | CA12CA1CA2CA9PRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719765-A2 | Phenylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-03 | — | — | EP | disclosed |