Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987463 | 0.92 | MAPT (0.44) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987636 | 0.86 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EPOLB | |
| Iodide SCHEMBL8987612 | 0.85 | MAPT (0.46) | MAPTMEN1KMT2AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8987633 | 0.84 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987684 | 0.84 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987678 | 0.82 | MMP2 (0.52) | MAPTMEN1KMT2AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8987710 | 0.82 | KDM4E (0.43) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987569 | 0.80 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987648 | 0.79 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL8987549 | 0.77 | MAPT (0.49) | MAPTMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719765-A2 | Phenylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-03 | — | — | EP | disclosed |