Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988013 | 0.90 | RIOK2 (0.48) | EPHX2LTA4HRIOK2MCHR1CSNK1D | |
| SCHEMBL8987760 | 0.89 | LTA4H (0.44) | EPHX2LTA4HKDRANO1SMN1; SMN2 | |
| SCHEMBL8987736 | 0.88 | SMN1; SMN2 (0.44) | RIOK2CSNK1DSMN1; SMN2MAPK10ALDH1A1 | |
| SCHEMBL8987904 | 0.86 | CSNK1D (0.47) | EPHX2LTA4HRIOK2CSNK1DRORC | |
| SCHEMBL8987787 | 0.83 | RIOK2 (0.50) | EPHX2LTA4HRIOK2CSNK1DRORC | |
| SCHEMBL8987800 | 0.83 | LTA4H (0.46) | EPHX2LTA4HKDRANO1SMN1; SMN2 | |
| SCHEMBL8987854 | 0.82 | RIOK2 (0.48) | EPHX2LTA4HRIOK2CSNK1DRORC | |
| SCHEMBL8987654 | 0.82 | RIOK2 (0.51) | EPHX2LTA4HRIOK2MCHR1CSNK1D | |
| SCHEMBL8988044 | 0.82 | MAPK10 (0.44) | RIOK2MCHR1CSNK1DRORCSMN1; SMN2 | |
| SCHEMBL8987987 | 0.79 | RIOK2 (0.47) | EPHX2LTA4HRIOK2CSNK1DRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |