Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988013 | 0.90 | RIOK2 (0.48) | CSNK1DRIOK2LTA4HEPHX2TEK | |
| SCHEMBL8987795 | 0.89 | MAPK10 (0.47) | CSNK1DRIOK2LTA4HEPHX2KDR | |
| SCHEMBL8987985 | 0.88 | MAPK10 (0.47) | CSNK1DRIOK2MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8987685 | 0.86 | EPHX2 (0.47) | CSNK1DRIOK2LTA4HEPHX2TEK | |
| SCHEMBL8987787 | 0.85 | RIOK2 (0.50) | CSNK1DRIOK2LTA4HEPHX2TEK | |
| SCHEMBL8987854 | 0.83 | RIOK2 (0.48) | CSNK1DRIOK2LTA4HEPHX2TEK | |
| SCHEMBL8987654 | 0.83 | RIOK2 (0.51) | CSNK1DRIOK2LTA4HEPHX2TEK | |
| SCHEMBL8987987 | 0.80 | RIOK2 (0.47) | CSNK1DRIOK2LTA4HEPHX2TEK | |
| SCHEMBL8987780 | 0.79 | RIOK2 (0.46) | CSNK1DRIOK2LTA4HEPHX2MAPK10 | |
| SCHEMBL8987704 | 0.78 | EPHX2 (0.51) | CSNK1DRIOK2LTA4HEPHX2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |