Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987662 | 0.86 | MMP2 (0.38) | KCNH2MAPK14MEN1KMT2A | |
| SCHEMBL8987719 | 0.85 | SMN1; SMN2 (0.39) | CYP17A1CYP2C9CYP2C19CNR2KDM4C | |
| SCHEMBL8987967 | 0.83 | KDM4C (0.36) | CYP17A1CYP2C9CYP2C19KDM4CRXRA | |
| SCHEMBL8987645 | 0.83 | KDM4C (0.38) | CYP17A1CYP2C9CYP2C19CNR2KDM4C | |
| SCHEMBL8988097 | 0.83 | KDM4C (0.36) | CYP17A1CYP2C9CYP2C19CNR2KDM4C | |
| SCHEMBL8987843 | 0.82 | MAPK14 (0.41) | MAPK14 | |
| SCHEMBL8987991 | 0.81 | KDM4C (0.37) | CYP17A1CYP2C9CYP2C19KDM4CRXRA | |
| SCHEMBL8988049 | 0.81 | KDM4C (0.37) | CYP17A1CYP2C9CYP2C19CNR2KDM4C | |
| SCHEMBL8987794 | 0.81 | CACNA1G (0.37) | CYP2C19CNR2CACNA1GCACNA1HKCNH2 | |
| SCHEMBL8987915 | 0.81 | BUB1 (0.41) | CYP2C19KDM4CRXRASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |