Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987866 | 0.89 | ALDH1A1 (0.46) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8987904 | 0.89 | CSNK1D (0.47) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1LTA4H | |
| SCHEMBL8987800 | 0.87 | LTA4H (0.46) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8987760 | 0.85 | LTA4H (0.44) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8987985 | 0.84 | MAPK10 (0.47) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8987841 | 0.82 | MAPK14 (0.50) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8987749 | 0.82 | LTA4H (0.46) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8987613 | 0.81 | ANO1 (0.47) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8988002 | 0.81 | MAPK14 (0.49) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A | |
| SCHEMBL8987856 | 0.80 | SMN1; SMN2 (0.45) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |