Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987794 | 0.96 | CACNA1G (0.37) | SCN9AKDM4CCACNA1GCACNA1HCACNA1I | |
| SCHEMBL8987785 | 0.87 | PROKR1 (0.38) | SCN9APROKR1KCNH2MAP3K12 | |
| SCHEMBL8987729 | 0.83 | TSHR (0.41) | SCN9APROKR1KCNH2 | |
| SCHEMBL8987993 | 0.82 | SCN9A (0.37) | SCN9APROKR1KCNH2MAP3K12 | |
| SCHEMBL8988077 | 0.82 | TNK2 (0.46) | MAPTCYP1A2CYP2C19MAP3K12 | |
| SCHEMBL8987719 | 0.82 | SMN1; SMN2 (0.39) | SCN9AKDM4CSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8988097 | 0.80 | KDM4C (0.36) | KDM4CSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8987967 | 0.80 | KDM4C (0.36) | KDM4CSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8987645 | 0.80 | KDM4C (0.38) | SCN9AKDM4CSMN1; SMN2MEN1MAPT | |
| SCHEMBL8987811 | 0.79 | TSHR (0.40) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |