Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | LIPE | Q05469 | 5/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987785 | 0.96 | PROKR1 (0.38) | SCN9AKDRBRAFMAP3K12MMP2 | |
| SCHEMBL8987811 | 0.88 | TSHR (0.40) | SCN9A | |
| SCHEMBL8988077 | 0.87 | TNK2 (0.46) | KDRBRAFMAP3K12FFAR4 | |
| SCHEMBL8987794 | 0.86 | CACNA1G (0.37) | SCN9AMAP3K12KCNH2 | |
| SCHEMBL8987828 | 0.86 | GAA (0.39) | SCN9AMMP2MMP9 | |
| SCHEMBL8987729 | 0.84 | TSHR (0.41) | SCN9AKCNH2PROKR1 | |
| SCHEMBL8987790 | 0.84 | LIPE (0.40) | SCN9ABRAFMMP2MMP9KCNH2 | |
| SCHEMBL8988017 | 0.82 | SCN9A (0.37) | SCN9AMAP3K12KCNH2PROKR1 | |
| SCHEMBL8987860 | 0.82 | SCN9A (0.38) | SCN9ABRAFMMP2MMP9KCNH2 | |
| SCHEMBL8988022 | 0.81 | MMP2 (0.38) | SCN9ABRAFMMP2MMP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |