Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899606 | 0.76 | P2RX7 (0.38) | P2RX7PTGER1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4874101 | 0.69 | CHRNA7 (0.42) | CHRNA7MAPK14P2RX7HTR2AHTR2C | |
| SCHEMBL19532054 | 0.64 | IDO1 (0.47) | MAPK14HTR2AHTR2C | |
| SCHEMBL3298107 | 0.63 | IDO1 (0.58) | MAPK14HTR2AHTR2C | |
| SCHEMBL19484584 | 0.62 | IDO1 (0.42) | MAPK14PTGER1 | |
| SCHEMBL25692948 | 0.62 | IDO1 (0.48) | HTR2AHTR2C | |
| SCHEMBL5408353 | 0.62 | PTGER1 (0.39) | PTGER1HTR2AHTR2C | |
| SCHEMBL3125030 | 0.61 | MDM2 (0.46) | PTGER1CYP1A2 | |
| SCHEMBL20548426 | 0.60 | MAPT (0.43) | — | |
| SCHEMBL16016318 | 0.58 | MPO (0.41) | MAPK14P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621907-A1 | FUNGICIDAL IMIDAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012044650-A1 | FUNGICIDAL IMIDAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |