SCHEMBL8988148

SCHEMBL8988148

C=C(C)C(=O)OC(O)(O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
KCNN4 O15554 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 2/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 4/20 0.37
CES1 P23141 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALOX15 P16050 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11876274 0.84 CYP2C19 (0.43) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL435821 0.83 ELANE (0.45) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL3180129 0.83 CYP2C19 (0.46) ELANEKCNN4CYP2C19HIF1ACYP1A2
Bicarbonate SCHEMBL27420408 0.81 ELANE (0.44) ELANEKCNN4CYP2C19HIF1ACYP1A2
Acetic Acid SCHEMBL28277118 0.81 ELANE (0.44) ELANEKCNN4CYP2C19HIF1ACYP1A2
Phosphine SCHEMBL27261108 0.81 ELANE (0.44) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL1153548 0.81 ELANE (0.44) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL3393201 0.81 ALDH1A1 (0.48) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL3422929 0.81 ELANE (0.44) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL26544633 0.81 CYP2C19 (0.41) ELANEKCNN4CYP2C19HIF1ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576137-A PHOTOLITHOGRAPHY AGFA-GEVAERT AG (DE) 1996-11-19 US disclosed