Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22708676 | 0.88 | MLYCD (0.51) | MLYCDMAOBMAPTLMNAKMT2A | |
| SCHEMBL28777 | 0.86 | MLYCD (0.54) | MLYCDLMNARECQLKMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL7476159 | 0.84 | MLYCD (0.53) | MLYCDLMNARECQLKMT2ANPC1 | |
| SCHEMBL3303829 | 0.80 | HPGD (0.56) | MLYCDACHEKMT2ANPC1RAB9A | |
| Bicarbonate SCHEMBL10585721 | 0.76 | GLA (0.58) | TNFRSF1AMAOBMAPTCYP1B1BCHE | |
| SCHEMBL4449884 | 0.76 | MAPT (0.56) | MLYCDMAPTLMNANPC1RAB9A | |
| Acetic Acid SCHEMBL3883980 | 0.74 | GLA (0.61) | TNFRSF1AMAOBMAPTCYP1B1BCHE | |
| Acetone SCHEMBL28318720 | 0.74 | GLA (0.61) | TNFRSF1AMAOBMAPTCYP1B1BCHE | |
| Acetic Acid SCHEMBL3883987 | 0.74 | GLA (0.61) | TNFRSF1AMAOBMAPTCYP1B1BCHE | |
| SCHEMBL30037936 | 0.74 | UNG (0.54) | MLYCDMAOBBCHEKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494918-A | ANTICHOLESTEROL AGENTS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5385912-A | Hypocholesterolemic or hypolipidemic agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-01-31 | — | — | US | disclosed |
| WO-1992015579-A1 | MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHETASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-09-17 | — | — | WO | disclosed |