Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45816 | 0.92 | MAPT (0.39) | MAPTCACNA1BAPBA1 | |
| SCHEMBL10607687 | 0.91 | MAPT (0.38) | MAPTCACNA1BAPBA1 | |
| Ammonia Solution, Strong SCHEMBL1614584 | 0.91 | MAPT (0.38) | MAPTCACNA1BAPBA1 | |
| SCHEMBL9715183 | 0.91 | MAPT (0.38) | MAPTCACNA1BAPBA1 | |
| Monoethanolamine SCHEMBL10816531 | 0.87 | CASP1 (0.32) | MAPTCACNA1BAPBA1 | |
| Ether SCHEMBL6277729 | 0.84 | TDP1 (0.34) | MAPTCACNA1BAPBA1 | |
| SCHEMBL10607690 | 0.78 | MAPT (0.36) | MAPTCACNA1BAPBA1 | |
| SCHEMBL9715188 | 0.78 | MAPT (0.36) | MAPTCACNA1BAPBA1 | |
| SCHEMBL87407 | 0.77 | CASP1 (0.36) | MAPTCACNA1BAPBA1 | |
| SCHEMBL87406 | 0.77 | RECQL (0.42) | MAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565146-A | Light duty liquid detergent compositions | COLOGATE-PALMOLIVE CO. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0509608-B1 | Light duty liquid detergent compositions | COLGATE PALMOLIVE CO (US) | 1996-07-10 | — | — | EP | disclosed |
| US-5480586-A | WITH LINEAR AKKYL BENZENE SULFONATE/ALKYL ETHER SULFATE ANIONIC SURFACTANTS, ALKYL ETHER POLYGLUCOSIDE, ALKANOLAMIDE FOAM STABILIZER; HANDWASHING DISHWARE | COLGATE-PALMOLIVE CO. (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0509608-A2 | Light duty liquid detergent compositions | Colgate-Palmolive Company (US) | 1992-10-21 | — | — | EP | disclosed |