SCHEMBL9715183

SCHEMBL9715183

C=CCOC(=O)C(CC(N)=O)S(=O)(=O)O.[NaH].[NaH]

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
CYP3A4 P08684 1/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607687 1.00 MAPT (0.38) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL45816 0.98 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
Ammonia Solution, Strong SCHEMBL1614584 0.97 MAPT (0.38) MAPTCACNA1BAPBA1CYP3A4TSHR
Monoethanolamine SCHEMBL8988330 0.91 MAPT (0.34) MAPTCACNA1BAPBA1
Ether SCHEMBL6277729 0.89 TDP1 (0.34) MAPTCACNA1BAPBA1TSHRTDP1
SCHEMBL2937128 0.84 CASP1 (0.35) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL5457190 0.84 CASP1 (0.35) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL4244326 0.84 RECQL (0.41) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL568267 0.84 RECQL (0.41) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL9715188 0.83 MAPT (0.36) MAPTCACNA1BAPBA1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0191631-B1 COATING SURFACES THE DOW CHEMICAL COMPANY (US) 1992-07-15 EP disclosed
EP-0192403-B1 FORMATION OF SOLID POLYMERIC MATERIAL THE DOW CHEMICAL COMPANY (US) 1989-07-19 EP disclosed
EP-0315466-A2 Formation of flexible laminates THE DOW CHEMICAL COMPANY (US) 1989-05-10 EP disclosed
US-4781781-A LATEX, SAND FILLER, XANTHAN GUM, SETTING ZURCHEM INVESTMENT MANAGEMENT INC., 1209 OWEN STREET, WILMINGTON, DELAWARE, A COMP. OF DE 1988-11-01 US disclosed
US-4722954-A Formation of solid polymeric material comprising a latex and a filler mixture of silica and xanthan gum DOW CHEMICAL COMPANY, THE, 2030 DOW CENTER, ABBOTT ROAD, MIDLAND, MICHIGAN 48640 1988-02-02 US disclosed
US-4692271-A PUMPABLE MIXTURES; LAMELLAR PHASE ALBRIGHT & WILSON LTD. (GB) 1987-09-08 US disclosed
EP-0192403-A1 Formation of solid polymeric material THE DOW CHEMICAL COMPANY (US) 1986-08-27 EP disclosed
US-4231912-A AN ALKYL ALKOXY SULFOSUCCINAMATE AS FOAMING AGENT COWX HENRY 1980-11-04 US disclosed