Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.49 |
| ▸ | F2 | P00734 | 7/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988648 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BF2PRSS1PLG | |
| SCHEMBL8988580 | 0.88 | HRH3 (0.43) | ITGB3ITGA2BHRH3HTR2C | |
| Hydrochloric Acid SCHEMBL8988671 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL8988764 | 0.85 | F2 (0.39) | ITGB3ITGA2BF2PRSS1PLG | |
| SCHEMBL8988516 | 0.84 | HRH3 (0.40) | HRH3HTR2C | |
| Hydrochloric Acid SCHEMBL7272547 | 0.82 | ITGB3 (0.53) | ITGB3ITGA2BF2PRSS1PLG | |
| SCHEMBL7283038 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BF2PRSS1PLG | |
| SCHEMBL7274287 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL7282064 | 0.80 | F10 (0.52) | ITGB3ITGA2BF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL7274330 | 0.80 | ITGB3 (0.53) | ITGB3ITGA2BF2PRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |