Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 8/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988580 | 0.88 | HRH3 (0.43) | HRH3HTR2CROCK2CTSDHTR2B | |
| SCHEMBL8988588 | 0.84 | ITGB3 (0.49) | HRH3HTR2C | |
| SCHEMBL8988443 | 0.84 | MMP1 (0.42) | HRH3 | |
| Hydrochloric Acid SCHEMBL7275455 | 0.82 | HRH3 (0.40) | HRH3FAAHFKBP1AADRB2ADRB1 | |
| SCHEMBL31615163 | 0.78 | HRH3 (0.47) | HRH3FAAHCTSDADRB2ADRB1 | |
| SCHEMBL31615164 | 0.78 | HRH3 (0.47) | HRH3FAAHCTSDADRB2ADRB1 | |
| SCHEMBL31615138 | 0.76 | HRH3 (0.47) | HRH3FAAHROCK2ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL8577042 | 0.75 | HRH3 (0.35) | HRH3ADRB2ADRB1GPR88EPHX2 | |
| SCHEMBL8910777 | 0.75 | HRH3 (0.39) | HRH3FAAHFKBP1AADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL8988698 | 0.73 | ITGB3 (0.42) | HRH3ROCK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |