Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD5 | P21918 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9567644 | 0.98 | IDO1 (0.61) | IDO1CA1CA2CA4CA6 | |
| SCHEMBL30590854 | 0.81 | CA1 (0.61) | CA1CA2CA4CA6ALOX15 | |
| Brocresine SCHEMBL635454 | 0.81 | IDO1 (0.54) | IDO1CA1CA2CYP3A4 | |
| SCHEMBL25580256 | 0.81 | IDO1 (0.54) | IDO1CA1CA2CYP3A4 | |
| Brocresine SCHEMBL29466825 | 0.81 | IDO1 (0.54) | IDO1CA1CA2CYP3A4 | |
| SCHEMBL22307818 | 0.79 | CA1 (0.58) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL5316598 | 0.78 | TAAR1 (0.66) | ALOX15MAPK1ALDH1A1TDP1PTGS1 | |
| SCHEMBL3807966 | 0.77 | TRPA1 (0.58) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL8435872 | 0.77 | CA1 (0.56) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL18975546 | 0.77 | CA1 (0.56) | CA1CA2CA4CA6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504076-A | Cephalosporin compounds | PFIZER INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0289002-B1 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |