Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.52 |
| ▸ | IGF1R | P08069 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590854 | 0.81 | CA1 (0.61) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL22307818 | 0.79 | CA1 (0.58) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL3807966 | 0.77 | TRPA1 (0.58) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL18975546 | 0.77 | CA1 (0.56) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL8988644 | 0.77 | IDO1 (0.60) | CA1CA2CA4CA6KDM4E | |
| Hydrochloric Acid SCHEMBL9567644 | 0.76 | IDO1 (0.61) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL11532845 | 0.72 | KDM4E (0.55) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL108093 | 0.72 | CA1 (1.00) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL30631592 | 0.72 | ALOX15 (0.80) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL107956 | 0.72 | ALOX15 (0.80) | CA1CA2CA4CA6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936083-A | BACTERICIDES | Uclaf, Roussel (FR) | 1999-08-10 | — | — | US | disclosed |
| US-5504076-A | Cephalosporin compounds | PFIZER INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0289002-B1 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |