Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988938 | 1.00 | TRPA1 (0.33) | TRPA1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8988971 | 0.85 | CSNK1D (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL8989148 | 0.82 | TRPA1 (0.35) | TRPA1ALDH1A1 | |
| SCHEMBL8989154 | 0.82 | TRPA1 (0.35) | TRPA1ALDH1A1 | |
| SCHEMBL8988782 | 0.82 | TRPA1 (0.33) | TRPA1ALDH1A1 | |
| SCHEMBL8988777 | 0.82 | TRPA1 (0.33) | TRPA1ALDH1A1 | |
| SCHEMBL8988956 | 0.81 | TRPA1 (0.32) | TRPA1ALDH1A1 | |
| SCHEMBL8988966 | 0.81 | TRPA1 (0.32) | TRPA1ALDH1A1 | |
| SCHEMBL8989061 | 0.80 | TRPA1 (0.33) | TRPA1ALDH1A1 | |
| SCHEMBL8988976 | 0.80 | ALDH1A1 (0.33) | TRPA1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488140-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5294734-A | 1-phosphato-4-amino-pent-2-enoic acids and derivatives | CIBA-GEIGY CORP. (US) | 1994-03-15 | — | — | US | disclosed |