Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989074 | 0.90 | HSD17B10 (0.38) | CTSBHSD17B10HPRT1LMNAL3MBTL1 | |
| SCHEMBL8989015 | 0.88 | SMN1; SMN2 (0.39) | LMNAL3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8989096 | 0.86 | ALDH1A1 (0.40) | CTSBPOLBALDH1A1KDM4ETDP1 | |
| SCHEMBL8989077 | 0.85 | KMT2A (0.39) | HSD17B10LMNAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL8988946 | 0.85 | CYP2D6 (0.30) | — | |
| SCHEMBL8989021 | 0.84 | HTT (0.44) | HSD17B10HTT | |
| SCHEMBL8989027 | 0.83 | HSD17B10 (0.33) | CTSBHSD17B10LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8988939 | 0.83 | CYP2D6 (0.32) | — | |
| SCHEMBL8989026 | 0.83 | CTSB (0.38) | CTSBHSD17B10HPRT1LMNAL3MBTL1 | |
| SCHEMBL8989033 | 0.83 | CTSB (0.38) | CTSBHSD17B10HPRT1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488140-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5294734-A | 1-phosphato-4-amino-pent-2-enoic acids and derivatives | CIBA-GEIGY CORP. (US) | 1994-03-15 | — | — | US | disclosed |