Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989763 | 0.93 | DRD3 (0.53) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7781043 | 0.88 | DRD2 (0.62) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL8989692 | 0.88 | DRD2 (0.48) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7781796 | 0.87 | DRD2 (0.55) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7781094 | 0.87 | DRD2 (0.60) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7781226 | 0.86 | SIGMAR1 (0.45) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7781116 | 0.85 | DRD2 (0.46) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7781080 | 0.85 | DRD2 (0.49) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL8989698 | 0.84 | DRD2 (0.45) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL8989708 | 0.83 | DRD2 (0.52) | DRD2DRD3DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521209-A | N-substituted azabicyclo[3.2.0]heptane derivatives as neuroleptics, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |