Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000505 | 1.00 | HSD17B10 (0.40) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL31000524 | 1.00 | HSD17B10 (0.40) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL2255624 | 1.00 | HSD17B10 (0.40) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL8989992 | 1.00 | HSD17B10 (0.40) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL21285786 | 1.00 | HSD17B10 (0.40) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL29233906 | 0.87 | HSD11B1 (0.44) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL29233907 | 0.87 | HSD11B1 (0.44) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL30334785 | 0.87 | HSD11B1 (0.44) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL34473203 | 0.87 | UCHL1 (0.39) | HSD17B10NR1H2UCHL1CHRM2CHRM1 | |
| SCHEMBL8989868 | 0.87 | PIK3CA (0.40) | HSD17B10NR1H2UCHL1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578633-A | VASOPRESSIN AND OXYTOCIN ANTAGONISTS | SANOFI (FR) | 1996-11-26 | — | — | US | disclosed |
| US-5481005-A | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present | SANOFI (FR) | 1996-01-02 | — | — | US | disclosed |
| US-5397801-A | Affinity for vasopressin and ocytocin receptors; disorders of nervous, cardiovascular and gastrointestinal systems | SANOFI (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5338755-A | Have affinity for vasopressin and ocytocin receptors; intermediates for drugs that act on central nervous system | ELF SANOFI (FR) | 1994-08-16 | — | — | US | disclosed |