Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29513232 | 1.00 | CYP19A1 (0.46) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL8932055 | 0.98 | CYP19A1 (0.44) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL1841101 | 0.98 | SMN1; SMN2 (0.47) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL16830262 | 0.90 | CYP19A1 (0.40) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL588692 | 0.83 | ESR2 (0.44) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL5728797 | 0.82 | CYP19A1 (0.43) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL13863637 | 0.82 | CYP1A1 (0.45) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL30252315 | 0.82 | CYP19A1 (0.43) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL20631601 | 0.81 | ALDH1A1 (0.42) | CYP19A1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL28716705 | 0.81 | GLA (0.43) | CYP19A1SMN1; SMN2ALDH1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2783 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736448-A | Coordination polymer based on iron hydrogenase and preparation method and application thereof | 南京晓庄学院 | 2024-03-22 | — | — | CN | claimed |
| CN-117700368-A | Synthesis method of pentanitrogen guanidine salt chiral phase transfer catalyst | 四川大学 | 2024-03-15 | — | — | CN | claimed |
| CN-117285477-A | Synthesis process and device of letrozole | 河南康达制药有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117024416-A | Hemicyanine compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116855100-A | Triphenylamine dye capable of being directly used for latent fingerprint development and preparation method and application thereof | 青岛科技大学 | 2023-10-10 | — | — | CN | claimed |
| CN-115521228-B | BChE and HDAC double-target inhibitor and preparation method and application thereof | 中国药科大学 | 2023-08-22 | — | — | CN | claimed |
| CN-114149421-B | Palmatine derivatives, preparation method and antithrombotic use thereof | 中国医学科学院医药生物技术研究所 | 2023-04-25 | — | — | CN | claimed |
| CN-115536597-A | Preparation method of high-purity alogliptin benzoate intermediate | 山东新华制药股份有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-114354802-A | Method for analyzing contents of two cyano bromobenzyl isomers in alogliptin benzoate | 山东大学 | 2022-04-15 | — | — | CN | claimed |
| CN-114149421-A | Palmatine derivative, preparation method and antithrombotic application thereof | 中国医学科学院医药生物技术研究所 | 2022-03-08 | — | — | CN | claimed |
| CN-102718673-A | Novel technology for synthesis of aminomethylbenzoic acid | JIANG CHANG | 2012-10-10 | — | — | CN | claimed |
| CN-102321102-A | N2,N4-disubstituted-2H,4H-pyrrole[1,2-b][1,2,4,6] thiatriazine-1,1,3-triketone derivatives as well as preparation and application thereof | UNIV SHANDONG | 2012-01-18 | — | — | CN | claimed |
| CN-102174318-A | Synthesis and application of activity-based permeable membrane fluorescent small molecular probe for in-vivo marking of protein tyrosine phosphatase | UNIV HUAZHONG SCIENCE TECH | 2011-09-07 | — | — | CN | claimed |
| CN-101407455-A | Preparation method of 4, 4' -stilbene dicarboxylic acid | DALIAN RES AND DESIGN INST OF (CN) | 2009-04-15 | — | — | CN | claimed |
| CN-1688298-A | Composition, Synthesis and Therapeutic Use of Polyamines | MURPHY MICHAEL A (US) | 2005-10-26 | — | — | CN | claimed |
| CN-1173938-C | Alpha-substitution of unprotected beta-amino ester compounds | ���µ�˹ҩ�﹫˾ | 2004-11-03 | — | — | CN | claimed |
| CN-1334799-A | Alpha-substitution of unprotected beta-amino ester compounds | AVENTIS PHARM PROD INC (US) | 2002-02-06 | — | — | CN | claimed |
| US-6140508-A | USEFUL IN THE PREPARATION OF FARNESYL-PROTEIN TRANSFERASE INHIBITORS. | MERCK & CO., INC. (US) | 2000-10-31 | — | — | US | claimed |
| WO-2000001674-A1 | PROCESS FOR MAKING 1,5-DISUBSTITUTED IMIDAZOLES | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | claimed |
| US-5565602-A | REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | claimed |