Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667152 | 0.89 | TDP1 (0.67) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL28025801 | 0.86 | TDP1 (0.64) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL29586362 | 0.86 | TDP1 (0.64) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL56317 | 0.84 | SRC (0.70) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL170040 | 0.84 | SRC (0.67) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL23674188 | 0.82 | NPC1 (0.61) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL23457197 | 0.81 | TDP1 (0.57) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL600680 | 0.81 | TDP1 (0.57) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL1581315 | 0.79 | SRC (0.76) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL22125607 | 0.78 | L3MBTL1 (0.53) | TDP1L3MBTL1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016031-A | Imidazoles [1,3,5] compound in triazine class and its preparation method and application that amide groups replaces | 浙江工业大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-105777609-A | Preparation method of 7-benzoyl-1, 3-indoline-2-ketone | 南京工业大学 | 2016-07-20 | — | — | CN | disclosed |
| EP-0716600-A1 | TOPICALLY ADMINISTRABLE COMPOSITIONS CONTAINING 3-BENZOYLPHENYLACETIC ACID DERIVATIVES FOR TREATMENT OF OPHTHALMIC INFLAMMATORY DISORDERS | ALCON LABORATORIES, INC. (US) | 1996-06-19 | — | — | EP | disclosed |
| WO-1995033457-A1 | TOPICALLY ADMINISTRABLE COMPOSITIONS CONTAINING 3-BENZOYLPHENYLACETIC ACID DERIVATIVES FOR TREATMENT OF OPHTHALMIC INFLAMMATORY DISORDERS | ALCON LABORATORIES, INC. (US) | 1995-12-14 | — | — | WO | disclosed |
| US-4313949-A | Method of producing an inhibitory effect on blood platelet aggregation | A. H. ROBINS COMPANY, INC. (US) | 1982-02-02 | — | — | US | disclosed |