SCHEMBL1667152

SCHEMBL1667152

O=C(c1ccccc1)C(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
LMNA P02545 4/20 0.64
CES2 O00748 3/20 0.64
CES1 P23141 3/20 0.64
SRC P12931 1/20 0.61
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MDM2 Q00987 1/20 0.48
CYP2D6 P10635 1/20 0.48
TSHR P16473 2/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.45
MITF O75030 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025801 0.98 TDP1 (0.64) TDP1L3MBTL1LMNACES2CES1
SCHEMBL29586362 0.98 TDP1 (0.64) TDP1L3MBTL1LMNACES2CES1
SCHEMBL56317 0.91 SRC (0.70) TDP1L3MBTL1LMNACES2CES1
SCHEMBL8990032 0.89 TDP1 (0.59) TDP1L3MBTL1LMNACES2CES1
SCHEMBL23457197 0.87 TDP1 (0.57) TDP1L3MBTL1LMNACES2CES1
SCHEMBL600680 0.87 TDP1 (0.57) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11387985 0.86 TDP1 (0.52) TDP1L3MBTL1LMNACES2CES1
SCHEMBL1669184 0.85 CES2 (0.55) TDP1L3MBTL1LMNACES2CES1
SCHEMBL22125607 0.83 L3MBTL1 (0.53) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11387982 0.83 ANPEP (0.54) TDP1L3MBTL1LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108060308-B Method and device for separating lithium from lithium-containing solution 中南大学 2020-01-03 CN claimed
CN-108060308-A A kind of method and device of the separating Li from lithium-containing solution 中南大学 2018-05-22 CN claimed
CN-115215727-B High energy efficiency preparation method of alkali metal alkoxide 赢创运营有限公司 2024-03-01 CN disclosed
CN-115215728-B High energy efficiency preparation method of alkali metal alkoxide 赢创运营有限公司 2024-02-09 CN disclosed
CN-115215728-A High-energy-efficiency preparation method of alkali metal alkoxide 赢创功能性解决方案有限公司 2022-10-21 CN disclosed
CN-108060308-B Method and device for separating lithium from lithium-containing solution 中南大学 2020-01-03 CN disclosed
CN-108060308-A A kind of method and device of the separating Li from lithium-containing solution 中南大学 2018-05-22 CN disclosed
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-7816020-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2010-10-19 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
US-20080093984-A1 Organic Electroluminescent Device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2008-04-24 US disclosed
US-20080093984-A1 Organic Electroluminescent Device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2008-04-24 US disclosed
US-20080093984-A1 Organic Electroluminescent Device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2008-04-24 US disclosed
CN-101088046-A Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2007-12-12 CN disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed
US-6458972-B1 THERMAL CLEAVAGE OF MACROCYCLIC ESTERS IN THE PRESENCE OF A THERMOSTABLE BENZENE DERIVATIVE HAARMANN & REIMER GMBH (DE) 2002-10-01 US disclosed
US-20020095045-A1 Process for the preparation of macrocyclic esters SYMRISE GMBH & CO., KG (DE) 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020095045-A1 Process for the preparation of macrocyclic esters CYP3A4, CYP4A11, CASP14 TDP1 2295/4885L3MBTL1 3796/4885LMNA 503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.