Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410307 | 0.77 | ALDH1A1 (0.52) | ALDH1A1GRIN1GRIN2BTAAR1TSHR | |
| SCHEMBL7442647 | 0.73 | ALDH1A1 (0.62) | ALDH1A1ADRA1ASLC6A3SMN1; SMN2MAPT | |
| SCHEMBL8393618 | 0.72 | ALDH1A1 (0.61) | ALDH1A1GRIN1GRIN2BTAAR1TSHR | |
| SCHEMBL21966469 | 0.71 | ALDH1A1 (0.53) | ALDH1A1GRIN1GRIN2BTAAR1TSHR | |
| SCHEMBL28775033 | 0.71 | GRIN1 (0.61) | ALDH1A1GRIN1GRIN2BTAAR1TSHR | |
| SCHEMBL23366564 | 0.70 | TSHR (0.69) | GRIN1GRIN2BTAAR1TSHRLMNA | |
| Acetic Acid SCHEMBL7431776 | 0.70 | ALDH1A1 (0.70) | ALDH1A1LMNAADRA1ASLC6A3SMN1; SMN2 | |
| Acetone SCHEMBL3486840 | 0.70 | ALDH1A1 (0.70) | ALDH1A1LMNAADRA1ASLC6A3SMN1; SMN2 | |
| SCHEMBL6882189 | 0.70 | ALDH1A1 (0.57) | ALDH1A1TAAR1ADRA1ASLC6A3SMN1; SMN2 | |
| SCHEMBL3103042 | 0.69 | GRIN1 (0.50) | ALDH1A1GRIN1GRIN2BTAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563250-A | Cleavable conjugates for the delivery and release of agents in native form | NEORX CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5141648-A | Methods for isolating compounds using cleavable linker bound matrices | NEORX CORPORATION (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0318948-B1 | CLEAVABLE IMMUNOCONJUGATES FOR THE DELIVERY AND RELEASE OF AGENTS IN NATIVE FORM | NEORX CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5017693-A | Methods for introducing a sulfhydryl amino or hydroxyl groups to a compound | NEORX CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0318948-A2 | Cleavable immunoconjugates for the delivery and release of agents in native form | NEORX CORPORATION (US) | 1989-06-07 | — | — | EP | disclosed |