SCHEMBL8990163

SCHEMBL8990163

O=C1CNNC(=S)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiohydantoin SCHEMBL31955553 0.70
SCHEMBL5385257 0.70
SCHEMBL1343779 0.69
SCHEMBL17234292 0.68
Thiohydantoin SCHEMBL28357993 0.67 GSK3A (0.31)
Thiobarbituric SCHEMBL16027 0.65
Thiobarbituric SCHEMBL31059040 0.65 GSK3A (0.38)
Hydantoin SCHEMBL5656545 0.65 CRBN (0.41)
Thiohydantoin SCHEMBL1976347 0.64
SCHEMBL18528446 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096903-A FUNGICIDAL TRISUBSTITUTED 1,2,4-TRIAZINE-3,5-DIONES BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US claimed
EP-0438717-A2 Trisubstituted 1,2,4-triazine-3,5-diones and intermediates BAYER AG (DE) 1991-07-31 EP claimed
EP-0168765-B1 PROCESS FOR THE PREPARATION OF S-SUBSTITUTED ISOTHIO UREAS MOBAY CORPORATION (US) 1989-08-16 EP claimed
EP-0284901-A1 3,4,6-Trisubstituted 1,2,4-triazin-5(4H)-ones BAYER AG (DE) 1988-10-05 EP claimed
US-4361437-A HERBICIDES, FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-30 US claimed
EP-0035833-A1 3-Thiooxo-5-oxo-hexahydro-1,2,4-triazine and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-09-16 EP claimed
JP-56115777-A None JP disclosed
EP-0509148-B1 Silver halide print-out material suitable as mounting aid and position proof AGFA GEVAERT NV (BE) 1996-07-17 EP disclosed
EP-0447688-B1 PHOTOGRAPHIC ROOMLIGHT MATERIALS CONTAINING HALOGEN ACCEPTORS AGFA-GEVAERT N.V. (BE) 1993-06-02 EP disclosed
EP-0509148-A1 Silver halide print-out material suitable as mounting aid and position proof AGFA-GEVAERT N.V. (BE) 1992-10-21 EP disclosed
US-5122434-A Silver chloride emulsion doped with group VII element AGFA-GEVAERT, N.V. (BE) 1992-06-16 US disclosed
US-5096903-A FUNGICIDAL TRISUBSTITUTED 1,2,4-TRIAZINE-3,5-DIONES BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
EP-0447688-A1 Photographic roomlight materials containing halogen acceptors AGFA-GEVAERT N.V. (BE) 1991-09-25 EP disclosed
EP-0284901-A1 3,4,6-Trisubstituted 1,2,4-triazin-5(4H)-ones BAYER AG (DE) 1988-10-05 EP disclosed
US-4361437-A HERBICIDES, FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-30 US disclosed
US-4361437-A HERBICIDES, FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-30 US disclosed
US-4361437-A HERBICIDES, FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-30 US disclosed
EP-0035833-A1 3-Thiooxo-5-oxo-hexahydro-1,2,4-triazine and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-09-16 EP disclosed
EP-0035833-A1 3-Thiooxo-5-oxo-hexahydro-1,2,4-triazine and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-09-16 EP disclosed
JP-S56115777-A 3-THIOOXO-5-OXO-HEXAHYDRO-1,2,4-TRIAZINE, ITS PREPARATION, HERBICIDE AND GERMICIDE COMPRISING IT AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1981-09-11 JP disclosed