Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobarbituric SCHEMBL16027 | 1.00 | — | — | |
| Thiobarbituric SCHEMBL2344775 | 0.97 | GSK3A (0.36) | GSK3AGSK3BCRBNMAPTITGB3 | |
| Thiobarbituric SCHEMBL8216351 | 0.97 | GSK3A (0.36) | GSK3AGSK3BCRBNMAPTITGB3 | |
| Thiobarbituric SCHEMBL2351184 | 0.97 | GSK3A (0.36) | GSK3AGSK3BCRBNMAPTITGB3 | |
| Barbituric Acid SCHEMBL4726594 | 0.91 | ALDH1A1 (0.44) | GSK3AGSK3BCRBNMAPTITGB3 | |
| Thiobarbituric SCHEMBL144675 | 0.87 | ITGB3 (0.33) | GSK3AGSK3BMAPTITGB3ITGB1 | |
| Thiobarbituric SCHEMBL7714190 | 0.87 | ALDH1A1 (0.42) | GSK3AGSK3BMAPTALDH1A1HPGD | |
| SCHEMBL8028070 | 0.85 | — | — | |
| Thiobarbituric SCHEMBL2455746 | 0.84 | ITGB3 (0.32) | GSK3AGSK3BITGB3ITGB1ITGAV | |
| Thiobarbituric SCHEMBL1867943 | 0.83 | ALDH1A1 (0.33) | GSK3AGSK3BITGB3ITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598101-B2 | KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-08-14 | — | — | EP | claimed |
| EP-2598101-B2 | KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-08-14 | — | — | EP | disclosed |