Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Methenamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methenamine SCHEMBL2878485 | 1.00 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL11043430 | 1.00 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL33785 | 0.93 | KDM4E (0.33) | KDM4E | |
| Methenamine SCHEMBL1229796 | 0.86 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL1157990 | 0.86 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL1538938 | 0.86 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL8519872 | 0.86 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL320310 | 0.86 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL1627716 | 0.86 | KDM4E (0.31) | KDM4E | |
| Methenamine SCHEMBL11683575 | 0.86 | KDM4E (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4601880-A | POLYMER, FORMALDEHYDE RELEASING COMPOUND | ALZA CORPORATION (US) | 1986-07-22 | — | — | US | claimed |
| US-5489281-A | Process for controlling pathogens in container | ALZA CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| US-5417676-A | Biocide dispensing device for use in container | ALZA CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |
| US-5417675-A | Antipathogen assembly | ALZA CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |
| US-5176665-A | ANTIMICROBIAL DEVICE FOR URINE DRAINAGE CONTAINER | ALZA CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| WO-1992012692-A1 | ANTIMICROBIAL DEVICE FOR URINE DRAINAGE CONTAINER | ALZA CORPORATION (US) | 1992-08-06 | — | — | WO | disclosed |
| US-4601880-A | POLYMER, FORMALDEHYDE RELEASING COMPOUND | ALZA CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| US-4529398-A | Method for preventing contamination of catheter and drainage receptacle | BUDDY L (HONG KONG), LTD., A CORP. OF HONG KONG | 1985-07-16 | — | — | US | disclosed |
| US-4464258-A | METHENAMINE | ALZA CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |
| US-4460367-A | Device containing biocide producing paraformalde and an acid | ALZA CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| US-4445889-A | Method for delivering an agent with biocidal activity in a body fluid receiving container | ALZA CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |