SCHEMBL8990195

SCHEMBL8990195

O=C(Cl)CC1CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957598 0.77
SCHEMBL23095576 0.77
SCHEMBL8957597 0.77
SCHEMBL19014082 0.75
SCHEMBL31119430 0.75
SCHEMBL25600600 0.75
SCHEMBL30877178 0.73 GRM2 (0.34)
SCHEMBL21535287 0.70 NR1H2 (0.40)
SCHEMBL19026687 0.70
SCHEMBL19009032 0.70 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0721451-A1 ACYLATED SULPHONAMIDES AS INSECTICIDES AND ACARICIDES Novartis AG (CH) 1996-07-17 EP disclosed
WO-1995009151-A1 ACYLATED SULPHONAMIDES AS INSECTICIDES AND ACARICIDES CIBA-GEIGY AG (CH) 1995-04-06 WO disclosed
US-5089662-A Miticides SCHERING AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-4983630-A Insecticides, miticides SCHERING AKTIENGESELLSCHAFT (DE) 1991-01-08 US disclosed
CN-1033271-A 2, the preparation method of 2-Difluocyclopropylethderivatives derivatives processes and as the purposes of sterilant SCHERING AG (DE) 1989-06-07 CN disclosed