Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661432 | 0.84 | ACHE (0.49) | ACHEMAOAMAOB | |
| SCHEMBL17135796 | 0.84 | ACHE (0.49) | ACHEMAOAMAOB | |
| SCHEMBL17147586 | 0.84 | ACHE (0.49) | ACHEMAOAMAOB | |
| SCHEMBL7699645 | 0.77 | ACHE (0.62) | ACHEMAOAMAOB | |
| SCHEMBL2047790 | 0.77 | ACHE (0.58) | ACHE | |
| SCHEMBL30834280 | 0.77 | ACHE (0.62) | ACHEMAOAMAOB | |
| SCHEMBL4199619 | 0.73 | ACHE (0.42) | ACHEMAOAMAOB | |
| SCHEMBL29621066 | 0.72 | ACHE (0.61) | ACHEIMPDH2IMPDH1 | |
| SCHEMBL3658017 | 0.72 | ACHE (0.61) | ACHEIMPDH2IMPDH1 | |
| SCHEMBL3742970 | 0.72 | ACHE (0.50) | ACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587107-B1 | Process for the preparation of substituted indanones | HOECHST AG (DE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0568879-B1 | Process for the preparation of substituted indanones and their use | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5360936-A | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| US-5329050-A | Process for the preparation of substituted indanones, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0587107-A1 | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0568879-A1 | Process for the preparation of substituted indanones and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-10 | — | — | EP | disclosed |