Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 5/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990292 | 0.87 | PIK3CD (0.36) | TACR1PNMTCHRNB2CHRNA4C5AR1 | |
| SCHEMBL8631852 | 0.80 | HCRTR2 (0.37) | TACR1PNMTCHRNB2CHRNA4P2RX7 | |
| SCHEMBL8990346 | 0.76 | OPRL1 (0.39) | IDO1 | |
| SCHEMBL8990464 | 0.75 | SLC6A2 (0.41) | C5AR1SLC6A2SLC6A4GRIN1GRIN2B | |
| SCHEMBL8990295 | 0.67 | OPRL1 (0.39) | TACR1 | |
| SCHEMBL8990466 | 0.66 | ESR2 (0.39) | C5AR1GRIN1GRIN2B | |
| SCHEMBL22816111 | 0.66 | HTR2C (0.57) | TACR1 | |
| SCHEMBL5523249 | 0.66 | IDO1 (0.38) | IDO1CHRNB2CHRNA4SLC6A2SLC6A4 | |
| SCHEMBL14833259 | 0.66 | MGLL (0.44) | FFAR4 | |
| SCHEMBL633462 | 0.65 | DHODH (0.38) | TACR1SLC6A4P2RX7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |