Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990446 | 0.83 | PDE10A (0.36) | SLC6A2SLC6A4SLC6A3PDE10AC5AR1 | |
| SCHEMBL30286722 | 0.83 | PDE10A (0.36) | SLC6A2SLC6A4SLC6A3PDE10AC5AR1 | |
| SCHEMBL27266235 | 0.80 | PDE10A (0.39) | PDE10AALDH1A1OPRL1 | |
| SCHEMBL8990282 | 0.75 | IDO1 (0.37) | SLC6A2SLC6A4C5AR1GRIN1GRIN2B | |
| SCHEMBL24460870 | 0.74 | HTR1A (0.60) | SLC6A2SLC6A4SLC6A3PDE10AGRIN1 | |
| SCHEMBL31067203 | 0.74 | KDM1A (0.38) | SLC6A2SLC6A4SLC6A3PDE10AHTR1A | |
| SCHEMBL24460957 | 0.74 | MMP2 (0.38) | PDE10AC5AR1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL8990472 | 0.74 | HTR2C (0.55) | MEN1KMT2A | |
| SCHEMBL8990466 | 0.72 | ESR2 (0.39) | PDE10AC5AR1GRIN1GRIN2BNAAA | |
| SCHEMBL14458711 | 0.72 | L3MBTL1 (0.39) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |