Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655417 | 0.77 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8990708 | 0.71 | ADORA1 (0.45) | ALDH1A1HPGDKDM4E | |
| SCHEMBL8990633 | 0.69 | CDK1 (0.47) | KMT2AMEN1MAPTKDM4E | |
| SCHEMBL8990610 | 0.69 | NPC1 (0.52) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31530565 | 0.68 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8990599 | 0.67 | HTT (0.46) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2997673 | 0.66 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8990578 | 0.65 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5025278 | 0.65 | KMT2A (0.47) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5026848 | 0.65 | KMT2A (0.47) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500428-A | Furyl-substituted purines and adenosine antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-03-19 | — | — | US | disclosed |
| US-5300509-A | Adenosine antagonists for treating cardiovascular disorders, vasodilation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-04-05 | — | — | US | disclosed |