Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 4/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751649 | 0.95 | GRM2 (0.49) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL8990631 | 0.93 | GRM2 (0.47) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL9737693 | 0.93 | GRM2 (0.47) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL9227374 | 0.90 | GRM2 (0.47) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL9221140 | 0.90 | GRM2 (0.48) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL9225207 | 0.89 | GRM2 (0.47) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL3173929 | 0.86 | ALOX5AP (0.45) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL3163945 | 0.86 | GRM2 (0.46) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL3157988 | 0.85 | GRM2 (0.45) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL8990674 | 0.84 | RARB (0.53) | GRM2ALOX5APFEN1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |